Test and Diagnosis of Genital warts

Genital warts is the human papillomavirus (HPV) infections caused by anal genital area proliferative damage as the main performance of sexually transmitted diseases. Most occurred in the 18 to 50-year-old young people. After about two weeks to eight months, an average of three months after the onset of incubation. The disease is more common, mainly spread through sexual contact.
1. The acetic acid white test
With 3% to 5% acetic acid solution treated with partial or wet for 5 to 10 minutes in the white area of ​​HPV infection, the so-called "acid white phenomenon." But specificity is not high, some chronic inflammation, such as Candida vulvitis, genital trauma and non-specific inflammation can cause false positive.
2. cytology
Wart with vaginal or cervical tissue smear, Papanicolaou stain, you can see two kinds of cells, namely cell vacuolization and dyskeratosis cells exist, for genital warts have diagnostic value.
3. Histopathological examination
As vacuoles of cells in the spinous layer and granular layer above, is an important diagnostic evidence of HPV infection.
The immunological tests
Using antibodies against HPV lesions in the HPV protein antigen. The method sensitivity is not high, the detection rate is only about 50%.
5. The nucleic acid hybridization test
It is an important means to detect HPV infection, including dot-blot (dot blot hybridization), in situ hybridization, nucleic acid blotting (Southern blot hybridization). The specificity and sensitivity of these methods are high, sensitive and reliable method for the diagnosis of HPV infection. But the cumbersome technical operations, generally carried out no clinically.
6. Polymerase chain reaction (PCR)

It is the most sensitive method of detection of HPV infection, but also make type-specific analysis, with high sensitivity, the method is simple and rapid characteristics. It has been widely used in clinical practice.